GLP-3 (RT)
Price range: $84.99 through $169.99
GLP-3 (RT) is Pantheon’s shorthand for the retatrutide research scaffold, a triple-receptor metabolic peptide acting at GIP, GLP-1 and glucagon receptors. It stands out for combining appetite, glucose and energy-expenditure pathways in one molecule.
Research focus: Body-weight regulation • Appetite & food-intake signaling • Energy expenditure • Glucose & insulin signaling
10mg, 20mg, 30mg | 10mg | GLP-3 (RT) | Laboratory Research Use Only
All compounds and products sold by Pantheon Formulas are strictly intended for in-vitro laboratory research and chemical analysis only. They are not for human or animal use, clinical trials, therapeutic application, food, or drug compounding.
You must be at least 21 years of age to purchase. By adding this item to your cart and proceeding to checkout, you certify that you are a qualified researcher, understand all laboratory handling procedures, and agree to our full Terms of Service.
All products currently listed on this site are for research purposes only and are not intended for human or veterinary consumption. This product is not a drug, food, supplement, or cosmetic, and is not intended to diagnose, treat, cure, or prevent any disease. Handling is restricted to qualified researchers in an appropriate laboratory setting. Nothing on this page constitutes a medical or therapeutic claim.
Research overview
GLP-3 (RT) is Pantheon’s shorthand for the retatrutide research scaffold, a triple-receptor metabolic peptide acting at GIP, GLP-1 and glucagon receptors. It stands out for combining appetite, glucose and energy-expenditure pathways in one molecule.
Proposed Effects & Research Interests
- Body-weight regulation — Human Phase 2 research reported large, dose-dependent reductions in body weight over 48 weeks.
- Appetite & food-intake signaling — GLP-1 and GIP pathway activity makes appetite regulation a central research area.
- Energy expenditure — Glucagon-receptor activity adds a thermogenic and energy-use component that differs from single GLP-1 agonists.
- Glucose & insulin signaling — Studied for improved glycemic control and insulin-related metabolic markers.
- Liver-fat & cardiometabolic research — Clinical substudies have examined hepatic fat, lipids, waist circumference and related metabolic markers.
How It Works
Retatrutide is designed to activate three incretin/metabolic receptors at once: GIPR + GLP-1R + glucagon receptor. The combination is intended to reduce energy intake while also influencing glucose handling and energy expenditure.
Evidence Snapshot
In a Phase 2 obesity trial, the highest studied exposure produced roughly 24% mean weight reduction at 48 weeks. Those results came from regulated clinical formulations and do not establish equivalence for an RUO vial.
Why Researchers Choose GLP-3 (RT)
Best suited to research comparing single-, dual- and triple-incretin signaling, weight regulation, appetite, glucose metabolism and liver-fat biology.
Product Details
| Strength | 10mg, 20mg, 30mg |
| Compound | GLP-3 (RT) |
| Research Class | Triple Receptor Agonist |
| Research Targets | GIP / GLP-1 / Glucagon Receptors |
| Form | Lyophilized Powder |
| Vial Size | 3mL |
Research Use Only
For laboratory research use only. Not for human or veterinary use. Proposed effects summarize published experimental or clinical research on the compound or its established research pathway; they are not directions for administration.
Frequently asked questions
It is a synthetic research compound supplied as a lyophilized (freeze-dried) material intended strictly for in-vitro analysis, molecular binding assays, and laboratory receptor studies.
Structural modifications (such as N-terminal alterations or sequence stabilization) are designed to hinder rapid enzymatic degradation in experimental assays, thereby extending half-life in laboratory observation models.
Investigational studies focus on target receptor affinity, somatotroph signaling cascades, downstream protein transcription, and comparative cellular stability against baseline fragments.
Every lot is subjected to third-party High-Performance Liquid Chromatography (HPLC) to verify ≥99% purity and Mass Spectrometry (MS) to confirm precise molecular mass identity. Full batch COAs are available on request.
Authentic Certificate of Analysis documentation ensures exact net peptide content calculations, eliminating variance in solvent reconstitution and enabling reproducible concentration metrics across trials.
This product is sold strictly for in-vitro research and laboratory use only. It is not intended for human or animal consumption, diagnostic purposes, or therapeutic application.
By purchasing this product, you confirm that you are a qualified researcher operating within an appropriate laboratory environment and will use this compound in accordance with all applicable local, state, and federal regulations.
Pantheon Formulas assumes no liability for misuse of this product outside of its intended research application.
GLP-3 (RT) is Pantheon’s shorthand for the retatrutide research scaffold, a triple-receptor metabolic peptide acting at GIP, GLP-1 and glucagon receptors. It stands out for combining appetite, glucose and energy-expenditure pathways in one molecule.
Proposed Effects & Research Interests
- Body-weight regulation — Human Phase 2 research reported large, dose-dependent reductions in body weight over 48 weeks.
- Appetite & food-intake signaling — GLP-1 and GIP pathway activity makes appetite regulation a central research area.
- Energy expenditure — Glucagon-receptor activity adds a thermogenic and energy-use component that differs from single GLP-1 agonists.
- Glucose & insulin signaling — Studied for improved glycemic control and insulin-related metabolic markers.
- Liver-fat & cardiometabolic research — Clinical substudies have examined hepatic fat, lipids, waist circumference and related metabolic markers.
How It Works
Retatrutide is designed to activate three incretin/metabolic receptors at once: GIPR + GLP-1R + glucagon receptor. The combination is intended to reduce energy intake while also influencing glucose handling and energy expenditure.
Evidence Snapshot
In a Phase 2 obesity trial, the highest studied exposure produced roughly 24% mean weight reduction at 48 weeks. Those results came from regulated clinical formulations and do not establish equivalence for an RUO vial.
Why Researchers Choose GLP-3 (RT)
Best suited to research comparing single-, dual- and triple-incretin signaling, weight regulation, appetite, glucose metabolism and liver-fat biology.
Product Details
| Strength | 10mg, 20mg, 30mg |
| Compound | GLP-3 (RT) |
| Research Class | Triple Receptor Agonist |
| Research Targets | GIP / GLP-1 / Glucagon Receptors |
| Form | Lyophilized Powder |
| Vial Size | 3mL |
Research Use Only
For laboratory research use only. Not for human or veterinary use. Proposed effects summarize published experimental or clinical research on the compound or its established research pathway; they are not directions for administration.
Frequently asked questions
Everything sold by Pantheon Formulas is intended strictly for laboratory and in-vitro research. Our products are not drugs, supplements, foods, or cosmetics, and are not for human or veterinary consumption. By purchasing, you confirm you're acquiring these materials for lawful research purposes.
Yes — every batch is independently tested by Janoshik Analytical, one of the most trusted third-party peptide labs in the industry. The Certificate of Analysis is included right in each product's image gallery, and the product description links directly to the official report on Janoshik's own site, so you can verify purity and identity straight from the source rather than taking our word for it. Need the COA for a specific lot? Reach out and we'll get it to you.
We accept major credit and debit cards as well as cryptocurrency, so you can check out whichever way works best for you. Every transaction is processed securely.
Orders are processed within 1–2 business days and ship via USPS, with most domestic orders arriving in roughly 2–5 business days depending on the service selected at checkout. You'll receive tracking the moment your order ships. We currently ship within the United States only — international shipping and an expanded product range are on the roadmap as Pantheon Formulas grows.
Discretion and product integrity are both priorities for us. Every order ships in fully unmarked, all-black packaging — the exterior gives no indication of what's inside. Within it, your vials are protected by multiple sealed layers: a sealed bubble-wrap sleeve, a tamper-evident rip-seal bag, a rigid inner box, and an outer mailer — with a fresh seal at every stage. Nothing branded appears until you open the inner box. It arrives discreet, protected, and clearly untampered.
We stand behind every order with a 30-day refund policy. If something arrives damaged, incorrect, or not to spec, contact us within 30 days and we'll make it right. For safety and integrity reasons, we're unable to accept returns on opened or unsealed vials.
Definitely — we're always happy to go deeper on anything we sell. Whether it's composition, purity, COAs, storage, handling, or shipping, just reach out through our contact page and a real person will get back to you. For independent reading and discussion, pathwaypeptide.com along with peptide-focused forums and subreddits are excellent places to dig in.
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